So my GF started a program of anti-depressants - Seroquel, Prozac, and Wellbutrin XL. 7 days ago she began, but within 2 days she had pretty much lost her appetite, and eating made her feel naseous. Over the weekend, she started to feel a little better, but then after one day of work at her over-loaded, ultra stressful job she pretty much fell apart. Last night she was sitting in a ball on the couch, curled up, rocking back and forth. I tried to get her to come to bed, but she said she was not sleepy. Eventually she did, but after I fell asleep she was back up and in the kitchen. She essentially told me she was feeling very suicidal, and to put all the knives in the house away... which I did. I got her back to bed, and she stayed all night. This morning she called, still a wreck. The psychiatrist she is seeing said to stop taking the Wellbutrin and Prozac, and take a Seroquel now (10:00 am) and one in 3 hours (about 1:00, 1.5 hours from now.) From my research I find that they all have a wide variety of side effects, and getting the dosage right can be a real lengthy process. It's hard for me to take care of her, because I work an hour away, but if she is going to try and kill herself I don't want that, either, and getting her locked up will do no good because she's not normally suicidal. Does anyone have any experience with these drugs? What can you tell me about experiences you've seen? Does this "stage" pass, or get worse, or ... what should I expect.