Blower + LensPen.
Funny story, a guy comes into where I work with a 70-200 2.8L II complaining that the pictures have specks all over them. I look at the font element and it's flawless, the lens is barely a week old, so I take the mount off and find thousands of little specks of kleenex on the back element and the felt lining the back chamber of the lens! The guy used tissues to clean the rear element of his lens! He said, "it felt soft enough on my nose, I didn't think it would hurt anything."
He asked if I could clean it off for him, I told him, "Sorry... that's going to take hours and hours..." and gave it back to him.
