When I did 1-ad before I took a dosage of 300mg in the first week and finished off at 500mg in the last week or two...going through 2 bottles. Went from 167-180 first time... and from 173-178lbs second time. First time, was terribly lethargic and libido went south by second week. Second time I took 4-ad along with it so really experienced no sides. This time I tried taking only 200mg throughout and experienced no sides. Despite eating relatively clean 4-5 days per week, my weight went up to 181lbs this morning. I was 178lbs before I started but weight did keep fluctuating to as low as 173lbs.