Of 592 719 patients with COVID-19 during the study period, 231 037 patients were included, of whom 62 727 were never vaccinated and 168 310 were fully vaccinated. Patients who were fully vaccinated were older and had more comorbidities (Table 1). In contrast, severe or critical COVID-19 was less common in the fully vaccinated group. The differences in age and comorbidities were reduced after weighting, while the severity of COVID-19 became less balanced. The median follow-up duration starting 30 days after COVID-19 was 90 days in the unvaccinated group and 84 days in the fully vaccinated group.
The composite outcome occurred in 31 unvaccinated patients and 74 fully vaccinated patients, with an incidence of 6.18 vs 5.49 per 1 000 000 person-days (Table 2). The adjusted risk was significantly lower in the fully vaccinated group (adjusted hazard ratio [aHR], 0.42; 95% CI, 0.29-0.62). The adjusted risk was significantly lower in fully vaccinated patients for both AMI (aHR, 0.48; 95% CI, 0.25-0.94) and ischemic stroke (aHR, 0.40; 95% CI, 0.26-0.63).
I’m not worrying about itToo bad. Lots of politicians and others had the false hope that the bivalent would halt transmission, thats why vax mandatrs remain in place many places. But unless we slow transmission, we will have mutations. Need to achieve the balance of slowing transmission to the point where new vaccines can be delivered in time.
I’m not worrying about it
The last time I was very nervous was in November with Omicron. We have yet to see anything like that. And even with omicron it was def more “mild” compared to delta.New variant 11 bility mutations this is it, we are done for. Hits immunity wall. Now show me a mutant that is growing like crazy in South Africa and/or India that is also killing a large portion of people under the age of 70 and I’m stocking up on the Stagg