Science ish dump thread

[Grape_Ape]

Serotonin Deficiency Directly Linked With Depression in Groundbreaking Study

New research in Biological Psychiatry offers the first direct evidence of diminished 5-HT release cements “serotonin hypothesis.” Researchers have postulated since the 1960s that major depression stems from disruptions in the serotonin neurotransmitter system. However, the evidence for that idea,

scitechdaily.com

 

[Grape_Ape]

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

www.news-medical.net

 

[pepsi]

Lasers revealed 5 ancient civilizations that were hiding in plain sight

Cutting-edge laser technology has allowed archaeologists to find the ruins of villages, ceremonial sites, and buildings hidden in dense forest.

ca.finance.yahoo.com

 

[Grape_Ape]

Earth Is About To See An Object Last Seen During The Time Of Neanderthals

The last time this was seen, humanity had only just begun to expand.

www.iflscience.com

 

[Ceaze]

Galactomannan is the most effective soluble dietary fiber in type 2 diabetes: a systematic review and network meta-analysis

Soluble dietary fibers are known to reduce blood glucose and lipid levels in patients with type 2 diabetes mellitus (type 2 diabetes). Although severa…

www.sciencedirect.com

Galactomannan was the most effective dietary fiber for reducing hemoglobin A1c, fasting blood glucose, triglyceride, and low-density lipoprotein cholesterol levels

 

[Ceaze]

Dead Bodybuilders Speaking from the Heart: An Analysis of Autopsy Reports of Bodybuilders That Died Prematurely

This study analyzed publicly available autopsy reports of male bodybuilders under the age of 50 who reportedly died from cardiovascular-related events. A general Google search with the terms “dead bodybuilders” was performed on 10 February 2022. Six reports were available for review and...

www.mdpi.com

 

[morrowalnut]

Serotonin Deficiency Directly Linked With Depression in Groundbreaking Study

New research in Biological Psychiatry offers the first direct evidence of diminished 5-HT release cements “serotonin hypothesis.” Researchers have postulated since the 1960s that major depression stems from disruptions in the serotonin neurotransmitter system. However, the evidence for that idea,

scitechdaily.com

Still don't think the hypothesis is very useful. Variation happens first at the level of genes. This affect neurotransmitters at the level of enzymes or receptors. Trying to compensate by blocking reuptake channels to increase intrasynapetic serotonin can work like a bandage can work on a lot of different kinds of cuts but.... Different cuts require different treatments in order to be really cured.


To me it looks like these variations show up in things like generation and destruction of methyltransferase, but I'm sure there are other gene variants that are relevant

 

[sans_pants]

Galactomannan is the most effective soluble dietary fiber in type 2 diabetes: a systematic review and network meta-analysis

Soluble dietary fibers are known to reduce blood glucose and lipid levels in patients with type 2 diabetes mellitus (type 2 diabetes). Although severa…

www.sciencedirect.com

Galactomannan was the most effective dietary fiber for reducing hemoglobin A1c, fasting blood glucose, triglyceride, and low-density lipoprotein cholesterol levels

is this not natural but some sort of supplement? and where do get?

 

[morrowalnut]

is this not natural but some sort of supplement? and where do get?

Galactomannans are polysaccharides consisting of a mannose backbone with galactose side groups, more specifically, a (1-4)-linked beta-D-mannopyranose backbone with branchpoints from their 6-positions linked to alpha-D-galactose, (i.e. 1-6-linked alpha-D-galactopyranose).

In order of increasing number of mannose-to-galactose ratio:[1]

• fenugreek gum, mannose:galactose ~1:1
• guar gum, mannose:galactose ~2:1
• tara gum, mannose:galactose ~3:1
• locust bean gum or carob gum, mannose:galactose ~4:1
• cassia gum, mannose:galactose ~5:1

 

[Grape_Ape]

 

[Grape_Ape]

 

[Grape_Ape]

An Organism That Can Dine Exclusively on Viruses Has Been Found in a World First

A type of freshwater plankton has become the first organism seen thriving on a diet of viruses, according to a new study by researchers from the University of Nebraska-Lincoln in the US.

www.sciencealert.com

 

[Grape_Ape]

The Remarkable Emptiness of Existence - Nautilus

Early scientists didn’t know it, but we do now: The void in the universe is alive.

nautil.us

 

[Grape_Ape]

Microbiome experts warn of an 'invisible extinction' that's harming human health

When Maria Gloria Dominguez-Bello travels to the Amazon jungle and tells villagers the reason for her visit, their first response is often laughter.

medicalxpress.com

 

[Grape_Ape]

US approves world’s first vaccine for honey bees - BBC News

The vaccine targets a disease known to weaken colonies by attacking bee larvae.

www.bbc.com

 

[Grape_Ape]

Study demonstrates safety and efficacy of a three-dose whole-parasite vaccine against malaria

A three-dose regimen of a whole-parasite vaccine against malaria – called Plasmodium falciparum sporozoite (PfSPZ) vaccine – demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria.

www.news-medical.net

 

[01ACRViper]

10 years too late for my dad

Boston cancer researchers create vaccine to kill and prevent brain cancer glioblastoma

Brigham and Women’s Hospital researchers have created a cancer vaccine to simultaneously kill and prevent the deadly brain cancer glioblastoma.

www.bostonherald.com

 

[Grape_Ape]

10 years too late for my dad

Boston cancer researchers create vaccine to kill and prevent brain cancer glioblastoma

Brigham and Women’s Hospital researchers have created a cancer vaccine to simultaneously kill and prevent the deadly brain cancer glioblastoma.

www.bostonherald.com

Sorry about your dad. I remember an interview where the Moderna CEO basically said something like stay alive most diseases could be solved within the next decade or so.

 

[Ceaze]

Burn an extra 100 cals per day by teabagging

Spoiler

Quantifying the benefits of inefficient walking: Monty Python inspired laboratory based experimental study - PubMed

For adults with no known gait disorder who average approximately 5000 steps/day, exchanging about 22%-34% of their daily steps with higher energy, low efficiency walking in Teabag style-requiring around 12-19 min-could increase daily EE by 100 kcal. Adults could achieve 75 minutes of vigorous...

pubmed.ncbi.nlm.nih.gov

 

[pepsi]

EU Market Outlook Says Solar Production Is Soaring

This article describes the rise of solar production in the EU, both for 2022 figures as well as for projecting outward to 2030.

cleantechnica.com

 

[pepsi]

 

[Grape_Ape]

The ozone layer was destroyed during Earth's biggest mass extinction

Fossils show plants were producing higher levels of sunscreen chemicals to protect against higher ultraviolet light levels at the end of the Permian period

www.newscientist.com

 

[Phil NJ]

The ozone layer was destroyed during Earth's biggest mass extinction

Fossils show plants were producing higher levels of sunscreen chemicals to protect against higher ultraviolet light levels at the end of the Permian period

www.newscientist.com

I remember how aerosols were destroying our o zone layer and we completely reversed that shit. Glad humanity got on the same page for that one.

Imagine if we were tasks to do that now lol

 

[Grape_Ape]

New Oral Drug Lowers Cholesterol by 70%

A team from University Hospitals and Case Western Reserve University has identified a small-molecule drug that effectively reduces cholesterol by 70% in animal models. PCSK9 inhibitors are the second most common type of medication used to manage cholesterol levels, following statins. These drugs

scitechdaily.com

 

[Grape_Ape]

New Research Indicates That Weak Muscles May Speed Up Aging

The study provides some of the first evidence of a link between muscle weakness and acceleration of biological age, according to researchers. People age at different rates due to a variety of intrinsic and extrinsic factors, which can affect their biological age and their risk of developing disease

scitechdaily.com