I decided to swap out my old Glock 21 for a newer 22 this weekend. I had to shoot a qualification course right after, and was alot happier with the .40. I wish I had gotten one sooner, I can actually fit my hand around the grip. I can't imagine many people can comfortably hold the Glock 21, it feels you're holding a farm tool. As I expected I also shot better since I could control it much better. I noticed it was a little more snappy than the .45 too. Thought I'd share my experience. The mags are a bitch to load though, my thumb is sore today.