Tugga
OT Supporter
- Status
4cd-Air
This user is longer available
- Oct 4, 2001
- 9,914
Formz
vr6dub can't cook chicken
Am J Gastroenterol. 2004 May;99(5):950-2.
Fulminant liver failure due to usnic acid for weight loss.
Durazo FA, Lassman C, Han SH, Saab S, Lee NP, Kawano M, Saggi B, Gordon S,
Farmer DG, Yersiz H, Goldstein RL, Ghobrial M, Busuttil RW.
Division of Digestive Diseases, Department of Medicin,; Dumont-UCLA Liver
Transplant Center, University of California, Los Angeles, California
90095-9302, USA.
The use of complementary and alternative medicine (CAM) in developed
countries has increased significantly over the years. Among the most popular
are the weight loss supplements or "fat burners." Liver failure due to these
popular remedies has been widely recognized. Usnic acid has been an
ingredient of dietary supplements that cause liver failure. Its
hepatotoxicity has not been recognized because it is usually mixed with
other ingredients that are presumably hepatotoxic. We describe a case of a
28-yr-old woman who presented with fulminant liver failure requiring
orthotopic liver transplantation, after taking pure usnic acid for weight
loss. This is the first report on fulminant liver failure associated with
the ingestion of pure usnic acid. A discussion about hepatotoxicity of the
different compounds of dietary supplements is presented. This is a reminder
for the clinicians about the potential side effects of CAM.
Publication Types:
Case Reports
PMID: 15128366 [PubMed - indexed for MEDLINE]
SOUNDS SAFE.
Fulminant liver failure due to usnic acid for weight loss.
Durazo FA, Lassman C, Han SH, Saab S, Lee NP, Kawano M, Saggi B, Gordon S,
Farmer DG, Yersiz H, Goldstein RL, Ghobrial M, Busuttil RW.
Division of Digestive Diseases, Department of Medicin,; Dumont-UCLA Liver
Transplant Center, University of California, Los Angeles, California
90095-9302, USA.
The use of complementary and alternative medicine (CAM) in developed
countries has increased significantly over the years. Among the most popular
are the weight loss supplements or "fat burners." Liver failure due to these
popular remedies has been widely recognized. Usnic acid has been an
ingredient of dietary supplements that cause liver failure. Its
hepatotoxicity has not been recognized because it is usually mixed with
other ingredients that are presumably hepatotoxic. We describe a case of a
28-yr-old woman who presented with fulminant liver failure requiring
orthotopic liver transplantation, after taking pure usnic acid for weight
loss. This is the first report on fulminant liver failure associated with
the ingestion of pure usnic acid. A discussion about hepatotoxicity of the
different compounds of dietary supplements is presented. This is a reminder
for the clinicians about the potential side effects of CAM.
Publication Types:
Case Reports
PMID: 15128366 [PubMed - indexed for MEDLINE]
SOUNDS SAFE.
TS
TS
Tugga
OT Supporter
TS
TS
Tugga
OT Supporter
Am J Gastroenterol. 2004 May;99(5):950-2.
Fulminant liver failure due to usnic acid for weight loss.
Durazo FA, Lassman C, Han SH, Saab S, Lee NP, Kawano M, Saggi B, Gordon S,
Farmer DG, Yersiz H, Goldstein RL, Ghobrial M, Busuttil RW.
Division of Digestive Diseases, Department of Medicin,; Dumont-UCLA Liver
Transplant Center, University of California, Los Angeles, California
90095-9302, USA.
The use of complementary and alternative medicine (CAM) in developed
countries has increased significantly over the years. Among the most popular
are the weight loss supplements or "fat burners." Liver failure due to these
popular remedies has been widely recognized. Usnic acid has been an
ingredient of dietary supplements that cause liver failure. Its
hepatotoxicity has not been recognized because it is usually mixed with
other ingredients that are presumably hepatotoxic. We describe a case of a
28-yr-old woman who presented with fulminant liver failure requiring
orthotopic liver transplantation, after taking pure usnic acid for weight
loss. This is the first report on fulminant liver failure associated with
the ingestion of pure usnic acid. A discussion about hepatotoxicity of the
different compounds of dietary supplements is presented. This is a reminder
for the clinicians about the potential side effects of CAM.
Publication Types:
Case Reports
PMID: 15128366 [PubMed - indexed for MEDLINE]
It is if used right
Formz
vr6dub can't cook chicken
I actually looked at this stuff for about an hour today. And some people were experiencing some really shitting sides at as little as 300mg. Some serious shit.
Formz
vr6dub can't cook chicken
if you want to get serious like the pros you will stack DNP with usnic and clen + t3 + t4
TS
TS
Tugga
OT Supporter
DNP is safer and more effective.
usnic acid is 50 times as potent as DNP in inhibiting liver oxidative phosphoralation.
Abomb
New Member
TS
TS
Tugga
OT Supporter
I would use DNP but going into summer in Australia and no A/C at my house is lethal.
TS
TS
Tugga
OT Supporter
TS
TS
Tugga
OT Supporter
they are mechanistically the same, you run similar issues with usnic acid with the elevated risk of liver failure.
you could use low dose DNP, but really if using DNP, any stims or things that raise body temp you should get a window AC unit or keep ice packs on hand (its easy to cool off with a good ice pack)--- bags of frozen peas are a good cheap substitute for ice packs.
- Status